Ikem Ekwonu is slated to return at left tackle for Carolina in Week 2 on the road vs. Arizona after an appendectomy sidelined him. His presence should stabilize Bryce Young’s protection, correcting Week 1’s rough showing when Yosh Nijman struggled and the quarterback was pressured into three turnovers. Ekwonu’s return also reshapes the Panthers’ line dynamics and adds heft to an offense that needs cleaner pockets.

Ekwonu’s long-term status hinges on his 2025-26 arc, as Carolina picked up his fifth-year option with a cap hit over $17.5 million. He’ll battle Cardinals newcomer Josh Sweat in a pivotal matchup, testing the Panthers’ ability to protect and unlock the passing game. Nijman and Christensen remain in the mix, but Ekwonu’s health is the linchpin for Week 2 and beyond.

Panthers at Cardinals in Week 2 centers on containing Kyler Murray’s improv magic and slowing Budda Baker’s impact. Bryce Young will lean on Tetairoa McMillan as a rising Week 2 target after a solid opener, while Carolina tries to ride improved talent to a road win. A December shootout between these teams weighs on both sides: the key is discipline against Baker and converting long drives for Young.

Baker’s veteran versatility remains the anchor for Arizona’s defense, and Murray’s mobility keeps Carolina unsettled. For fantasy managers, Baker provides a stabilizing floor against a rookie, McMillan offers a cheap mid-round ceiling, and Murray’s volatility makes Cardinals’ pass-game options intriguing but risky.